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Brain mapping has forever altered and extended our understanding of the systems of the brain. The integrative capacity of brain maps enables the inclusion of a diverse array of observations and experimental results. Maps are used to describe brain structure, function, and connectivity, to catalog the ever-expanding knowledge base of human and animal nervous systems, to compare healthy tissue with diseased tissue, and to show detailed subsystems and circuits. Brain Mapping: The Systems is a compilation of the current research and developments in brain mapping. This book, the second in a series, provides an encyclopedic survey of brain maps characterizing the specific systems of the brain. It is a natural companion to Brain Mapping: The Methods because it describes the use of these techniques to create maps of the normal brain. It is an essential resource for all scientists, clinicians, and students interested in brain mapping. Key Features * Brings together the latest developments in brain mapping in one volume * Provides a detailed and chronological perspective of the field * Progresses from descriptions of underlying anatomic framework for mapping primary functional systems to more complex cognitive and emotional behaviors * Includes numerous full-color illustrations for comparing and contrasting brain structure and function * Allows for the integration of disparate information about the brain.
Brain mapping --- Brain Mapping --- Brain --- Magnetic Resonance Imaging --- methods --- anatomy & histology --- physiology --- Diagnostic Imaging --- Tomography --- Central Nervous System --- Investigative Techniques --- Diagnostic Techniques, Neurological --- Diagnostic Techniques and Procedures --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Nervous System --- Diagnosis --- Anatomy
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High Throughput Bioanalytical Sample Preparation: Methods and Automation Strategies is an authoritative reference on the current state-of-the-art in sample preparation techniques for bioanalysis. This book focuses on high throughput (rapid productivity) techniques and describes exactly how to perform and automate these methodologies, including useful strategies for method development and optimization. A thorough review of the literature is included within each of these chapters describing high throughput sample preparation techniques: protein removal by precipitation; equilibrium dialysis and ultrafiltration; liquid-liquid extraction; solid-phase extraction; and various on-line techniques. The text begins with an introductory overview of the role of bioanalysis in pharmaceutical drug development. Fundamental understanding of the strategies for sample preparation is reinforced next, along with essential concepts in extraction chemistry. Several chapters introduce and discuss microplates, accessory products and automation devices. Particular strategies for efficient use of automation within a bioanalytical laboratory are also presented. The subject material then reviews protein precipitation, liquid-liquid extraction, solid-phase extraction and various on-line sample preparation approaches. The book concludes with information on recent advances in sample preparation, such as solid-phase extraction in a card format and higher density extraction plates. Important objectives that can be accomplished when the strategies presented in this book are followed include: improved efficiency in moving discovery compounds to preclinical status with robust analytical methods; return on investment in automation for sample preparation; and improved knowledge and expertise of laboratory staff. Shows the reader exactly how to perform modern bioanalytical sample preparation techniques, complete with detailed strategies Thorough literature review and summary of published information Detailed discussion and examples of the method development process.
Drugs --- Pharmaceutical industry --- Metabolic Phenomena --- Pharmacological Phenomena --- Kinetics --- Natural Science Disciplines --- Investigative Techniques --- Fluids and Secretions --- Chemicals and Drugs --- Evaluation Studies as Topic --- Drug Discovery --- Body Fluids --- Chemistry --- Methods --- Drug Evaluation, Preclinical --- Chemistry Techniques, Analytical --- Metabolism --- Pharmacokinetics --- Pharmaceutical Preparations --- Biochemical Phenomena --- Phenomena and Processes --- Physiological Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Anatomy --- Disciplines and Occupations --- Chemical Phenomena --- Analysis --- Technological innovations
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Signal analysis and signal treatment are integral parts of all types of Nuclear Magnetic Resonance. In the last ten years, much has been achieved in the development of dimensional spectra. At the same time new NMR techniques such as NMR Imaging and multidimensional spectroscopy have appeared, requiring entirely new methods of signal analysis. Up until now, most NMR texts and reference books limited their presentation of signal processing to a short introduction to the principles of the Fourier Transform, signal convolution, apodisation and noise reduction. To understand the mathematics of the
Mathematics --- Nuclear magnetic resonance. --- Nuclear magnetic resonance. Signal theory (Telecommunication). --- Signal theory (Telecommunication). --- Nuclear magnetic resonance --- Signal theory (Telecommunication) --- Natural Science Disciplines --- Spectrum Analysis --- Computing Methodologies --- Chemistry Techniques, Analytical --- Disciplines and Occupations --- Information Science --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Signal Processing, Computer-Assisted --- Magnetic Resonance Spectroscopy
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Human medicine --- Business policy --- Acupuncture --- Small business --- Health Services Administration --- Morals --- Health Occupations --- Professional Practice --- Risk Management --- Investigative Techniques --- Safety --- Disciplines and Occupations --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Care --- Accident Prevention --- Psychology, Social --- Accidents --- Behavior and Behavior Mechanisms --- Public Health --- Psychiatry and Psychology --- Environment and Public Health --- Safety Management --- Private Practice --- Ethics --- Practice Management --- Methods --- Organization and Administration --- Practice --- Management
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This book represents an essential reference manual for all of the well-characterized leukemia-lymphoma cell lines currently available. It provides the most important facts, using the succinct and user-friendly format that has made the FactsBooks so popular with scientists and clinical researchers. Introductory chapters provide background and perspective for culturing malignant hematopoietic (blood forming) cell lines. These chapters are followed by over 400 comprehensive individual entries. Each cell line entry highlights essential clinical, immunological, genetic, and functional featur
Human histology. Human cytology --- Human medicine --- Cancer cells. --- Cell Line. --- Cell lines. --- Hematologic Neoplasms. --- Hematopoietic stem cells. --- Human cell culture. --- Leukemia. --- Leukemia, Experimental. --- Leukemia, Experimental--Handbooks, manuals, etc. Lymphomas--Handbooks, manuals, etc. Cancer cells--Handbooks, manuals, etc. Human cell culture--Handbooks, manuals, etc. Hematopoietic stem cells--Handb. --- Lymphoma. --- Lymphomas. --- Research. --- Tumor Cells, Cultured. --- Neoplasms by Histologic Type --- Lymphoproliferative Disorders --- Cells, Cultured --- Culture Techniques --- Neoplasms --- Lymphatic Diseases --- Cells --- Clinical Laboratory Techniques --- Immunoproliferative Disorders --- Anatomy --- Diseases --- Investigative Techniques --- Immune System Diseases --- Hemic and Lymphatic Diseases --- Cell Culture Techniques --- Leukemia --- Lymphoma --- Tumor Cells, Cultured --- Medicine --- Health & Biological Sciences --- Hematologic Diseases
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Physiotherapy. Alternative treatments --- Urology. Andrology --- Gynaecology. Obstetrics --- enuresis --- blaastraining --- kinesitherapie --- prolaps --- encopresis --- bekkenbodemdysfunctie --- bekkenbodem --- Pelvic Floor --- Evidence-Based Medicine. --- Exercise Therapy --- Pelvic Pain --- Uterine Prolapse --- Pelvic floor --- Urogynecology. --- Périnée --- Urogynécologie --- physiopathology. --- methods. --- rehabilitation. --- prevention & control. --- Diseases --- Physical therapy. --- Maladies --- Physiothérapie --- Urogynecology --- Physical therapy --- Evidence-Based Practice --- Physical Therapy Modalities --- Pelvis --- Investigative Techniques --- Pain --- Abdominal Muscles --- Therapeutics --- Pelvic Organ Prolapse --- Clinical Medicine --- Uterine Diseases --- Genital Diseases, Female --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Occupations --- Body Regions --- Signs and Symptoms --- Prolapse --- Muscle, Skeletal --- Medicine --- Anatomy --- Pathological Conditions, Anatomical --- Female Urogenital Diseases --- Disciplines and Occupations --- Muscles --- Pathological Conditions, Signs and Symptoms --- Musculoskeletal System --- Female Urogenital Diseases and Pregnancy Complications --- Rehabilitation --- Evidence-Based Medicine --- Methods
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